The microbiome has emerged as a critical regulator of tumor biology and immune response in lung cancer.

Pigment epithelium-derived factor (PEDF) is a potent endogenous immunomodulatory protein with anti-metastatic, anti-angiogenic, and anti-inflammatory properties, and has recently gained attention for its ability to target tumor cells across various cancers.

Anaplastic thyroid carcinoma (ATC) is a lethal subtype of thyroid cancer with a poor prognosis. Due to the lack of promising treatment opportunities for ATC, gaining a better understanding of the molecular mechanisms underlying tumorigenesis seems crucial.

The present study aims to investigate the allele and genotype frequencies of common TCF7L2 polymorphisms and their associations with T2DM in an elderly Iranian population.

This systematic review investigates how artificial intelligence (AI) and machine learning algorithms can optimize PRS (AI-optimized PRS) to improve cardiovascular disease prediction.

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is often therapeutically challenging.

نرخ ابتلا به سرطان تیروئید در ایران طی سال‌های اخیر افزایش چشمگیری داشته است.

This research investigates the frequency of UGT1A1 genetic variations in the Iranian population

Current in vitro models have played important roles in improving knowledge and understanding of cellular and molecular biology, but cannot exactly recapitulate the physiology of human tissues such as thyroid. In this article, we conducted a systematic review to present scientific and methodological time-trends of the reconstruction and generation of 3 D functional thyroid follicles and organoids for thyroid research in health and disease.

A better understanding of key regulatory pathways involved in cancers has led to the development of molecularly targeted therapies. Molecular profiling based on genomics, proteomics, and metabolomics in tumors provides clinicians with the necessary information to maintain a personalized therapeutic regimen according to the patient's needs